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Structure of 886510-09-4
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3-Fluoro-2-(trifluoromethyl)pyridine-4-carboxylic acid features a trifluoromethyl group and a fluorine substituent positioned for strong electron-withdrawal, enhancing its utility in medicinal chemistry. The carboxylic acid moiety enables direct coupling reactions, while the pyridine scaffold provides structural rigidity and improved metabolic stability. This compound serves as a key building block in the synthesis of bioactive molecules.
3-Fluoro-2-(trifluoromethyl)pyridine-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation of fluorinated heterocyclic motifs into API candidates. Its carboxylic acid functionality facilitates amide coupling, esterification, and derivatization under standard conditions. The molecule exhibits enhanced metabolic stability and modulates electronic properties via synergistic electron-withdrawing effects from the trifluoromethyl and fluorine substituents. Bench-stable and compatible with diverse reaction protocols, it functions as a key scaffold for developing kinase inhibitors and other bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: