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Structure of 886372-53-8
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4-Bromo-6-methylpyridine-2-carbonitrile features a pyridine core functionalized with bromo, methyl, and nitrile groups at strategic positions. This electron-deficient heterocycle integrates readily into cross-coupling reactions and serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. The nitrile moiety enhances reactivity in nucleophilic substitutions, while the bromine enables palladium-catalyzed transformations.
4-Bromo-6-methylpyridine-2-carbonitrile serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal functional groups. The bromo and nitrile moieties offer complementary reactivity for late-stage diversification, while the methyl group enhances metabolic stability. Its bench-stable crystalline form facilitates handling and purification, making it suitable for scalable synthesis of heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501
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Lot numbers can be found on the outside label of a product: