Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-bromo-2,6-dimethylpyridine

  • CAS No. 5093-70-9

  • Cat. No. CS-W019636
  • Purity≥95%
  • MDL No.MFCD00671475

*For research and further manufacturing use only, not for direct human use.

4-bromo-2,6-dimethylpyridine|CS-W019636

Structure of 5093-70-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 5093-70-9
  • Cat. No. CS-W019636
  • Purity ≥95%
  • MDL No. MFCD00671475
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BrN
  • Molecular Weight 186.05
  • Synonym(s) pyridine, 4-bromo-2,6-dimethyl-
  • SMILES CC1=CC(Br)=CC(C)=N1

Description

4-Bromo-2,6-dimethylpyridine features a sterically hindered pyridine core with electron-deficient character, enabling selective coupling reactions. The bromine at the 4-position serves as a reliable handle for palladium-catalyzed transformations, while methyl groups at C2 and C6 enhance stability and solubility in organic media.

Application

4-Bromo-2,6-dimethylpyridine serves as a versatile building block in medicinal chemistry and catalysis, enabling palladium-catalyzed cross-coupling reactions due to its stable bromine substituent and electron-deficient pyridine core. The 2,6-dimethyl groups provide steric protection and enhance bench stability, facilitating straightforward purification and scalability. It functions effectively in Suzuki-Miyaura, Stille, and Negishi couplings for constructing complex heterocyclic scaffolds and API intermediates.

Synthesis

  • Route1

    References

    • Roczniki Chemii, , vol. 33, p. 387,392 Chem.Abstr., , p. 18954
  • Route2

    References

    • Takalo, Harri; Pasanen, Paavo; Kankare, Jouko Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1988 , vol. 42, # 6 p. 373 - 377
  • Route3

    References

    • Murphy, Jaclyn M.; Liao, Xuebin; Hartwig, John F. Journal of the American Chemical Society, 2007 , vol. 129, # 50 p. 15434 - 15435

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.46094
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-bromo-2,6-dimethylpyridine sigma4-bromo-2,6-dimethylpyridine manufacturer4-bromo-2,6-dimethylpyridine price4-bromo-2,6-dimethylpyridine structure4-bromo-2,6-dimethylpyridine SDSbuy 4-bromo-2,6-dimethylpyridine4-bromo-2,6-dimethylpyridine supplier4-bromo-2,6-dimethylpyridine uses4-bromo-2,6-dimethylpyridine molecular weightprice of 4-bromo-2,6-dimethylpyridine4-bromo-2,6-dimethylpyridine chemical name formula of 4-bromo-2,6-dimethylpyridine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label