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CS-W001157 4
Total: USD 88.00

2,3-Dibromo-6-chloropyridine

  • CAS No. 885952-16-9

  • Cat. No. CS-W005894
  • Molecule weight271.34
  • Purity≥98%
  • MDL No.MFCD06798229

*For research and further manufacturing use only, not for direct human use.

2,3-Dibromo-6-chloropyridine|CS-W005894

Structure of 885952-16-9

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General Information

  • CAS No. 885952-16-9
  • Cat. No. CS-W005894
  • Purity ≥98%
  • MDL No. MFCD06798229
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₂Br₂ClN
  • Molecular Weight 271.34
  • Synonym(s) 2-CHLORO-5,6-DIBROMOPYRIDINE
  • SMILES ClC1=CC=C(Br)C(Br)=N1

Description

2,3-Dibromo-6-chloropyridine features a halogenated pyridine core with complementary reactivity at multiple positions. The electron-deficient aromatic ring enables efficient cross-coupling transformations, while the bromine and chlorine substituents offer orthogonal functionalization pathways. This bench-stable compound integrates readily into complex heterocyclic scaffolds under standard conditions.

Application

2,3-Dibromo-6-chloropyridine serves as a versatile building block in heterocyclic synthesis, enabling regioselective functionalization at the 2- and 3-positions via palladium-catalyzed cross-coupling reactions. The presence of two bromine atoms and a chlorine substituent provides orthogonal reactivity for sequential transformations, facilitating access to complex pyridine-based scaffolds. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P264-P270-P330-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.26
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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