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3-Bromoimidazo[1,2-a]pyridine-6-carbonitrile

  • CAS No. 885950-21-0

  • Cat. No. CS-0035914
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Bromoimidazo[1,2-a]pyridine-6-carbonitrile|CS-0035914

Structure of 885950-21-0

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General Information

  • CAS No. 885950-21-0
  • Cat. No. CS-0035914
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄BrN₃
  • Molecular Weight 222.04
  • Synonym(s) None
  • SMILES C1=CC2=NC=C(Br)N2C=C1C#N

Description

3-Bromoimidazo[1,2-a]pyridine-6-carbonitrile features a rigid fused heterocyclic core with complementary electrophilic (bromine) and nucleophilic (cyano) sites. This arrangement enables seamless integration into cross-coupling reactions and modular synthesis of bioactive imidazopyridine scaffolds under standard conditions.

Application

3-Bromoimidazo[1,2-a]pyridine-6-carbonitrile serves as a versatile heterocyclic building block for medicinal chemistry and catalytic cross-coupling. The bromine and nitrile groups enable sequential functionalization via palladium-catalyzed reactions, while the imidazopyridine core provides structural rigidity and favorable pharmacophore properties. Bench-stable and compatible with standard purification methods, it facilitates efficient synthesis of complex nitrogen-containing scaffolds relevant to drug discovery programs.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   41.09
  • LogP   1.96848
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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