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CS-W001157 4
Total: USD 88.00

(1R,2R)-2-(1-Pyrrolidinyl)cyclohexanamine

  • CAS No. 885677-92-9

  • Cat. No. CS-0091955
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1R,2R)-2-(1-Pyrrolidinyl)cyclohexanamine|CS-0091955

Structure of 885677-92-9

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General Information

  • CAS No. 885677-92-9
  • Cat. No. CS-0091955
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀N₂
  • Molecular Weight 168.28
  • Synonym(s) Cyclohexanamine, 2-(1-pyrrolidinyl)-, (1R,2R)-
  • SMILES N[C@H]1[C@H](N2CCCC2)CCCC1

Description

This chiral amine features a rigid cyclohexane scaffold with stereochemically defined (1R,2R) configuration, enabling precise control in asymmetric synthesis. The pendant pyrrolidinyl group imparts enhanced solubility and hydrogen-bonding capacity, while the secondary amine serves as a robust nucleophilic handle for conjugation or catalyst design under standard conditions.

Application

(1R,2R)-2-(1-Pyrrolidinyl)cyclohexanamine serves as a chiral bifunctional building block enabling stereoselective synthesis of bioactive molecules. Its rigid cyclohexane scaffold with defined stereochemistry provides consistent diastereoselectivity in asymmetric transformations. The primary amine and pyrrolidine moiety offer complementary reactivity for conjugate additions, metal-catalyzed couplings, and heterocycle construction, while exhibiting excellent bench stability and ease of purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.26
  • LogP   1.3521
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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