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Structure of 885518-97-8
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4-Bromo-6-iodo-1H-indazole features a dual-halogenated indazole core, enabling sequential cross-coupling reactions in the construction of complex heterocyclic architectures. The electron-deficient aromatic system facilitates efficient metal-catalyzed transformations, while the orthogonal reactivity of bromo and iodo substituents supports modular synthetic design. This compound serves as a key intermediate in medicinal chemistry and materials science applications requiring precise functionalization.
4-Bromo-6-iodo-1H-indazole serves as a versatile biaryl building block for palladium-catalyzed cross-coupling reactions, enabling efficient access to functionalized indazole scaffolds. The orthogonal halogen reactivity—bromine undergoing Suzuki-Miyaura coupling, iodine participating in Stille or Negishi transformations—facilitates sequential diversification. Bench-stable and readily purified by flash chromatography, it supports scalable synthesis of complex heterocycles relevant to medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: