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Structure of 885068-76-8
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This fluorinated arylacetic acid features a brominated phenyl ring conjugated to a difluoromethyl group, delivering enhanced metabolic stability and electron-withdrawing character. The para-bromine substitution enables efficient coupling in cross-coupling protocols, while the geminal difluoride imparts increased lipophilicity and resistance to enzymatic degradation. This compound serves as a key building block for bioactive molecule synthesis.
2-(3-Bromophenyl)-2,2-difluoroacetic acid serves as a versatile building block for fluorinated aromatic systems, enabling efficient incorporation of difluoromethyl and bromophenyl moieties into pharmaceutical and agrochemical scaffolds. Its bench-stable nature and compatibility with palladium-catalyzed cross-coupling reactions facilitate C–C bond formation under standard conditions. The molecule’s functional group tolerance supports downstream derivatization in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: