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Structure of 883986-76-3
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1-Methyl-1H-pyrrolo[2,3-b]pyridin-5-amine features a fused heterocyclic core with a methylated pyrrole nitrogen and an exocyclic amine, enabling strong hydrogen bonding and enhanced solubility. This electron-rich scaffold integrates readily into bioactive molecules, serving as a key building block for kinase inhibitors and fluorescent probes under standard conditions.
1-Methyl-1H-pyrrolo[2,3-b]pyridin-5-amine serves as a versatile heterocyclic building block for medicinal chemistry and catalytic synthesis. Its electron-rich pyrrolopyridine core enables efficient coupling reactions and functionalization at the C5 position. The N-methyl group enhances metabolic stability and modulates basicity, improving solubility and bioavailability. This scaffold exhibits robust bench stability and compatibility with standard purification techniques, facilitating integration into multi-step syntheses of kinase inhibitors and other pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: