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CS-W001157 4
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5-Amino-2,3-dihydrobenzofuran

  • CAS No. 42933-43-7

  • Cat. No. CS-B1174
  • Purity≥98%
  • MDL No.MFCD03617969

*For research and further manufacturing use only, not for direct human use.

5-Amino-2,3-dihydrobenzofuran|CS-B1174

Structure of 42933-43-7

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General Information

  • CAS No. 42933-43-7
  • Cat. No. CS-B1174
  • Purity ≥98%
  • MDL No. MFCD03617969
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO
  • Molecular Weight 135.16
  • Synonym(s) 2,3-Dihydrobenzofuran-5-amine; 2,3-Dihydro-1-benzofuran-5-amine
  • SMILES NC1=CC=C(OCC2)C2=C1

Description

5-Amino-2,3-dihydrobenzofuran delivers a reactive amino handle adjacent to a flexible dihydrofuran ring, enabling straightforward derivatization in medicinal chemistry. This scaffold integrates readily into bioactive molecules, offering enhanced solubility and metabolic stability compared to aromatic analogs.

Application

5-Amino-2,3-dihydrobenzofuran serves as a versatile scaffold for medicinal chemistry and synthetic intermediates, enabling direct functionalization at the amino group and aromatic ring. Its stable dihydrobenzofuran core exhibits favorable handling properties and compatibility with common coupling reactions, facilitating access to diverse heterocyclic architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.2037
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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