Fmoc-Hyp-OH

Name: Fmoc-Hyp-OH
Brand: ChemScene
Availability: InStock
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CAS No. 88050-17-3
Cat. No. CS-W008205
Purity≥98%
MDL No.MFCD00151929

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 88050-17-3

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General Information

CAS No. 88050-17-3
Cat. No. CS-W008205
Purity ≥98%
MDL No. MFCD00151929
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₀H₁₉NO₅
Molecular Weight 353.37
Synonym(s) Fmoc-L-Hydroxyproline
SMILES O=C([C@H]1N(C[C@@H](C1)O)C(OCC2C3=CC=CC=C3C4=CC=CC=C24)=O)O

Description

Fmoc-Hyp-OH is a bench-stable, moisture-tolerant amino acid derivative featuring a C-terminal hydroxyl group on a proline scaffold. This compound integrates seamlessly into solid-phase peptide synthesis workflows, delivering high coupling efficiency and enabling the incorporation of hydroxyproline residues with minimal epimerization.

Synthesis

Route1
- 28920-43-6
- In-stock
  
  51-35-4
- ~%
- In-stock
  
  88050-17-3
References
- Tetrahedron Letters, , vol. 35, # 51 p. 9509 - 9512
Route2
- In-stock
  
  82911-69-1
- ~%
- In-stock
  
  88050-17-3
References
- Organic Preparations and Procedures International, , vol. 30, # 2 p. 183 - 186
Route3
- 7536-89-2
- ~%
- In-stock
  
  88050-17-3
References
- Organic Preparations and Procedures International, , vol. 30, # 2 p. 183 - 186

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 87.07
LogP 2.4553
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 3

Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Fmoc

Building Blocks Functional Group Alcohol

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Proline and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

Catalysis Organocatalysts Asymmetric Organocatalysts

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Fmoc-Hyp-OH

CAS No. 88050-17-3

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