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Structure of 87883-17-8
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1-(5-Nitropyridin-3-yl)ethan-1-one features a pyridine ring bearing a nitro group at the 5-position and a ketone-functionalized ethyl side chain at the 3-position. This electron-deficient heterocycle integrates readily into cross-coupling reactions, serving as a key building block for bioactive nitrogen-containing scaffolds in medicinal chemistry.
1-(5-Nitropyridin-3-yl)ethan-1-one serves as a versatile building block in heterocyclic synthesis, enabling efficient access to functionalized pyridine derivatives. Its nitro and acetyl groups exhibit complementary reactivity, facilitating sequential transformations such as reduction, nucleophilic substitution, and coupling reactions. The molecule demonstrates good bench stability and compatibility with standard purification methods, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: