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CS-W001157 4
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Morpholine-2-carboxylic acid hydrochloride

  • CAS No. 878010-24-3

  • Cat. No. CS-0067952
  • Purity≥97%
  • MDL No.MFCD06410629

*For research and further manufacturing use only, not for direct human use.

Morpholine-2-carboxylic acid hydrochloride|CS-0067952

Structure of 878010-24-3

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General Information

  • CAS No. 878010-24-3
  • Cat. No. CS-0067952
  • Purity ≥97%
  • MDL No. MFCD06410629
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀ClNO₃
  • Molecular Weight 167.59
  • Synonym(s) morpholine-2-carboxylic acid,hydrochloride
  • SMILES O=C(C1CNCCO1)O.[H]Cl

Description

Morpholine-2-carboxylic acid hydrochloride offers a stable, moisture-tolerant platform for medicinal chemistry applications. The protonated morpholine ring enhances solubility and facilitates incorporation into peptide backbones. This derivative serves as a key scaffold in bioactive molecule design, particularly where polar, rigid motifs are required to modulate target engagement and pharmacokinetic properties.

Application

Morpholine-2-carboxylic acid hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its carboxylic acid functionality facilitates direct amidation and esterification, while the morpholine ring provides solubility and metabolic stability. The hydrochloride salt enhances crystallinity and shelf stability, simplifying handling and purification in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   -0.5188
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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