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Structure of 877133-58-9
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6-Chloro-4-iodopyridin-3-ol features a pyridine core bearing chlorine at C6 and iodine at C4, with a phenolic hydroxyl group at C3. This electron-deficient heterocycle enables direct functionalization in cross-coupling reactions, particularly Suzuki-Miyaura and Buchwald-Hartwig processes. The ortho-halogen arrangement facilitates regioselective transformations, while the bench-stable hydroxyl group supports derivatization under mild conditions.
6-Chloro-4-iodopyridin-3-ol serves as a versatile building block in the synthesis of functionalized pyridine derivatives. Its orthogonal halogenation pattern enables selective cross-coupling reactions, particularly Suzuki-Miyaura and Buchwald-Hartwig couplings, facilitating the construction of complex heterocyclic scaffolds. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H303-H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: