(5-(Methoxycarbonyl)-2-methylphenyl)boronic acid

Name: (5-(Methoxycarbonyl)-2-methylphenyl)boronic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 876189-18-3
Cat. No. CS-0042974
Purity≥95%
MDL No.MFCD11111429

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(5-(Methoxycarbonyl)-2-methylphenyl)boronic acid|CS-0042974

Structure of 876189-18-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 876189-18-3
Cat. No. CS-0042974
Purity ≥95%
MDL No. MFCD11111429
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₁BO₄
Molecular Weight None
Synonym(s) 5-Methoxycarbonyl-2-methylphenylboronic acid
SMILES OB(C1=CC(C(OC)=O)=CC=C1C)O

Description

This boronic acid features a methoxycarbonyl group at the 5-position and a methyl substituent at the 2-position, delivering enhanced solubility and stability under standard conditions. The para-directed electronic profile facilitates efficient Suzuki-Miyaura coupling reactions, enabling rapid construction of biaryl architectures in synthetic and medicinal chemistry workflows.

Application

(5-(Methoxycarbonyl)-2-methylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with retained ester functionality. Its bench-stable nature, compatibility with diverse reaction conditions, and tolerance for common functional groups facilitate straightforward synthesis of complex aromatic systems. The methyl and methoxycarbonyl substituents provide predictable electronic and steric modulation, enhancing utility in medicinal chemistry and materials science applications.

Synthesis

Route1
- In-stock
  
  90347-66-3
- ~71%
- In-stock
  
  876189-18-3
References
- Wang, Xiao-Jun; Sun, Xiufeng; Zhang, Li; Xu, Yibo; Krishnamurthy, Dhileepkumar; Senanayake, Chris H. Organic Letters, 2006 , vol. 8, # 2 p. 305 - 307
Route2
- 67-56-1
- In-stock
  
  170230-88-3
- ~%
- In-stock
  
  876189-18-3
References
- Pal, Arnab; Berube, Marie; Hall, Dennis G. Angewandte Chemie - International Edition, 2010 , vol. 49, # 8 p. 1492 - 1495

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 66.76
LogP -0.53858
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

876189-18-3 sigma876189-18-3 manufacturer876189-18-3 price876189-18-3 structure876189-18-3 SDSbuy 876189-18-3876189-18-3 supplier876189-18-3 uses876189-18-3 molecular weightprice of 876189-18-3876189-18-3 chemical name formula of 876189-18-3

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(5-(Methoxycarbonyl)-2-methylphenyl)boronic acid

CAS No. 876189-18-3

Recommended Products