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CS-W001157 4
Total: USD 88.00

2-Fluorophenylboronic acid pinacol ester

  • CAS No. 876062-39-4

  • Cat. No. CS-W023174
  • Purity≥97%
  • MDL No.MFCD05663874

*For research and further manufacturing use only, not for direct human use.

2-Fluorophenylboronic acid pinacol ester|CS-W023174

Structure of 876062-39-4

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General Information

  • CAS No. 876062-39-4
  • Cat. No. CS-W023174
  • Purity ≥97%
  • MDL No. MFCD05663874
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆BFO₂
  • Molecular Weight 222.06
  • Synonym(s) 2-(2-Fluorophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; 2-(2-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • SMILES CC1(C)C(C)(C)OB(C2=CC=CC=C2F)O1

Description

2-Fluorophenylboronic acid pinacol ester delivers a stable, bench-ready boronate handle for Suzuki-Miyaura cross-coupling reactions. The pinacol ester protects the boronic acid against oxidation and hydrolysis, enabling reliable coupling under standard conditions. This derivative integrates seamlessly into complex molecule assembly, particularly in medicinal chemistry and materials synthesis where fluorinated aryl motifs are required.

Application

2-Fluorophenylboronic acid pinacol ester serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. Its pinacol boronate ester functionality enhances air and moisture stability while enabling selective C–C bond formation under mild conditions. The fluorinated aryl group facilitates downstream functionalization and is compatible with diverse reaction partners, making it a practical reagent for constructing biaryl motifs in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   2.1249
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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