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CS-W001157 4
Total: USD 88.00

Canagliflozin impurity 23

  • CAS No. 214360-58-4

  • Cat. No. CS-W021407
  • Purity≥97%
  • MDL No.MFCD03453665

*For research and further manufacturing use only, not for direct human use.

Canagliflozin impurity 23|CS-W021407

Structure of 214360-58-4

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General Information

  • CAS No. 214360-58-4
  • Cat. No. CS-W021407
  • Purity ≥97%
  • MDL No. MFCD03453665
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆BFO₂
  • Molecular Weight 222.07
  • Synonym(s) None
  • SMILES CC1(C)OB(OC1(C)C)C1=CC=C(F)C=C1

Description

This boronate ester features a 4-fluorophenyl group attached to a stable dioxaborolane core, enabling reliable cross-coupling in Suzuki-Miyaura reactions. The tetramethyl substitution enhances shelf life and resistance to hydrolysis under standard conditions.

Synthesis

  • Route1
    • null|null
      61676-62-8
    • null|null
      460-00-4
    • ~99%
    • In-stock
      Canagliflozin impurity 23|CS-W021407
      214360-58-4

    References

    • Murray, Philip R. D.; Browne, Duncan L.; Pastre, Julio C.; Butters, Chris; Guthrie, Duncan; Ley, Steven V. Organic Process Research and Development, 2013 , vol. 17, # 9 p. 1192 - 1208
  • Route2
    • In-stock
      2,3-Dimethylbutane-2,3-diol|CS-0015356
      76-09-5
    • null|null
      22092-92-8
    • null|null
      459-45-0
    • ~59%
    • In-stock
      Canagliflozin impurity 23|CS-W021407
      214360-58-4

    References

    • UNIVERSITE DE BORDEAUX 1; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; PUCHEAULT, Mathieu Jonathan Damien; MARCIASINI, Ludovic Daniel Alain; VAULTIER, Michel Patent: WO2014/9169 A1, 2014 ; Location in patent: Page/Page column 60 ;
  • Route3
    • In-stock
      Bis(pinacolato)diborane|CS-D1216
      73183-34-3
    • null|null
      460-00-4
    • ~%
    • In-stock
      Canagliflozin impurity 23|CS-W021407
      214360-58-4

    References

    • WO2011/149950 A2, ; Page/Page column 136-137 ; WO 2011/149950 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   2.1249
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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