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CS-W001157 4
Total: USD 88.00

(1R,3S)-Cyclopentane-1,3-dicarboxylic acid

  • CAS No. 876-05-1

  • Cat. No. CS-0070727
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

(1R,3S)-Cyclopentane-1,3-dicarboxylic acid|CS-0070727

Structure of 876-05-1

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Description

This chiral cyclopentane-1,3-dicarboxylic acid features a rigid, cis-configured scaffold ideal for probing stereochemical effects in medicinal chemistry. The proximal carboxylate groups enable straightforward derivatization and coordination in metal-ligand systems. Bench-stable and moisture-tolerant, it integrates seamlessly into synthetic routes requiring defined spatial orientation.

Application

(1R,3S)-Cyclopentane-1,3-dicarboxylic acid serves as a valuable chiral building block in the synthesis of bioactive molecules and natural product analogs. Its defined stereochemistry enables predictable stereoselective transformations, while the dicarboxylic acid functionality offers versatile handles for derivatization, including esterification, amide formation, and metal coordination. The compound exhibits excellent bench stability and facilitates efficient purification via recrystallization or chromatography, making it well-suited for use in medicinal chemistry campaigns and catalyst development.

General Information

  • CAS No. 876-05-1
  • Cat. No. CS-0070727
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀O₄
  • Molecular Weight 158.15
  • Synonym(s) cis-1,3-Cyclopentanedicarboxylic acid
  • SMILES O=C(O)[C@@H](CC1)C[C@@H]1C(O)=O

Computational Chemistry Data

  • TPSA   74.6
  • LogP   0.5719
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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