Lot numbers can be found on the outside label of a product:
N-Bocamino-cyano-acetic acid ethyl ester
-
CAS No. 865370-16-7
- Cat. No. CS-0035554
- Purity≥97%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 865370-16-7
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 865370-16-7
- Cat. No. CS-0035554
- Purity ≥97%
- MDL No. None
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₀H₁₆N₂O₄
- Molecular Weight 228.25
- Synonym(s) tert-butyl(ethoxycarbonyl)(cyano)methylcarbamate
- SMILES CCOC(=O)C(C#N)N=C(O)OC(C)(C)C
Description
N-Bocamino-cyano-acetic acid ethyl ester features a protected amine and dual reactive handles—cyano and ester—enabling direct incorporation into peptide backbones or conjugation workflows. The Boc group ensures stability during synthetic manipulations, while the ethyl ester facilitates selective hydrolysis or coupling under mild conditions. This derivative serves as a key building block for non-natural amino acids and bioconjugates in medicinal chemistry.
Application
N-Bocamino-cyano-acetic acid ethyl ester serves as a versatile building block for the synthesis of cyano-containing heterocycles and amino acid derivatives. Its stability under standard reaction conditions, combined with orthogonal functional group compatibility, enables efficient incorporation into peptide-like scaffolds and pharmaceutical intermediates via nucleophilic addition, cyclization, or palladium-catalyzed coupling processes.
Synthesis
-
References
-
Poulsen, Thomas B.; Dickmeiss, Gustav; Overgaard, Jacob; Jorgensen, Karl Anker Angewandte Chemie - International Edition, 2008 , vol. 47, # 25 p. 4687 - 4690
-
-
Route2
-
105-56-6 -
In-stock
462100-44-3 - ~32%
-
In-stock
865370-16-7
References
-
Armstrong, Alan; Edmonds, Ian D.; Swarbrick, Martin E.; Treweeke, Nigel R. Tetrahedron, 2005 , vol. 61, # 35 p. 8423 - 8442
-
-
Route3
-
In-stock
24424-99-5 -
32683-02-6 - ~80%
-
In-stock
865370-16-7
References
-
He, Xinhua; Wang, Lili; Zheng, Zhibing; Xiao, Junhai; Zhong, Wu; Li, Song Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 553 - 557
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 91.91
- LogP 1.17078
- H_Acceptors 5
- H_Donors 1
- Rotatable_Bonds 3
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- N-Bocamino-cyano-acetic acid ethyl ester sigmaN-Bocamino-cyano-acetic acid ethyl ester manufacturerN-Bocamino-cyano-acetic acid ethyl ester priceN-Bocamino-cyano-acetic acid ethyl ester structureN-Bocamino-cyano-acetic acid ethyl ester SDSbuy N-Bocamino-cyano-acetic acid ethyl esterN-Bocamino-cyano-acetic acid ethyl ester supplierN-Bocamino-cyano-acetic acid ethyl ester usesN-Bocamino-cyano-acetic acid ethyl ester molecular weightprice of N-Bocamino-cyano-acetic acid ethyl esterN-Bocamino-cyano-acetic acid ethyl ester chemical name formula of N-Bocamino-cyano-acetic acid ethyl ester