Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Methoxybenzonitrile

  • CAS No. 874-90-8

  • Cat. No. CS-W013398
  • Purity≥98%
  • MDL No.MFCD00001818

*For research and further manufacturing use only, not for direct human use.

4-Methoxybenzonitrile|CS-W013398

Structure of 874-90-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 874-90-8
  • Cat. No. CS-W013398
  • Purity ≥98%
  • MDL No. MFCD00001818
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO
  • Molecular Weight 133.15
  • Synonym(s) 4-Methoxybenzonitrile, (p-Anisonitrile)
  • SMILES N#CC1=CC=C(OC)C=C1

Description

4-Methoxybenzonitrile features a para-substituted aromatic ring bearing both a methoxy and nitrile group, delivering enhanced solubility and stability in polar organic media. This dual-functional motif enables direct incorporation into pharmaceutical intermediates and functional materials without requiring protection steps.

Application

4-Methoxybenzonitrile serves as a versatile building block in medicinal chemistry and materials science, offering a robust platform for nucleophilic aromatic substitution and transition-metal-catalyzed coupling reactions. Its combination of electron-donating methoxy and electron-withdrawing nitrile groups enables predictable reactivity patterns. The compound exhibits excellent bench stability, facile purification, and compatibility with diverse functional groups, making it ideal for constructing heterocyclic scaffolds and API intermediates in high-throughput synthesis.

Synthesis

  • Route1

    References

    • Li, Dongmei; Shi, Feng; Guo, Shu; Deng, Youquan Tetrahedron Letters, 2005 , vol. 46, # 4 p. 671 - 674
  • Route2
    • null|null
      70978-37-9
    • ~98%
    • In-stock
      4-Methoxybenzonitrile|CS-W013398
      874-90-8

    References

    • Zhou, Wang; Zhang, Liangren; Jiao, Ning Angewandte Chemie, International Edition, 2009 , vol. 48, # 38 p. 7094 - 7097 Angewandte Chemie, 2009 , vol. 121, # 38 p. 7228 - 7231
  • Route3
    • null|null
      104-92-7
    • null|null
      68-12-2
    • ~83%
    • In-stock
      4-Methoxybenzonitrile|CS-W013398
      874-90-8

    References

    • Ishii, Genki; Moriyama, Katsuhiko; Togo, Hideo Tetrahedron Letters, 2011 , vol. 52, # 18 p. 2404 - 2406

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   33.02
  • LogP   1.56688
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Methoxybenzonitrile sigma4-Methoxybenzonitrile manufacturer4-Methoxybenzonitrile price4-Methoxybenzonitrile structure4-Methoxybenzonitrile SDSbuy 4-Methoxybenzonitrile4-Methoxybenzonitrile supplier4-Methoxybenzonitrile uses4-Methoxybenzonitrile molecular weightprice of 4-Methoxybenzonitrile4-Methoxybenzonitrile chemical name formula of 4-Methoxybenzonitrile
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label