Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Methoxybenzamide

  • CAS No. 3424-93-9

  • Cat. No. CS-W022205
  • Purity≥98%
  • MDL No.MFCD00007995

*For research and further manufacturing use only, not for direct human use.

4-Methoxybenzamide|CS-W022205

Structure of 3424-93-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 3424-93-9
  • Cat. No. CS-W022205
  • Purity ≥98%
  • MDL No. MFCD00007995
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₂
  • Molecular Weight 151.16
  • Synonym(s) 4-Methoxybenzamide, (p-Anisamide)
  • SMILES O=C(N)C1=CC=C(OC)C=C1

Description

4-Methoxybenzamide features a para-methoxy group that enhances solubility and modulates electronic properties, enabling efficient integration into pharmaceutical intermediates. The amide functionality provides robust stability and facilitates directional coupling in synthetic sequences. This compound serves as a key building block for bioactive molecules requiring polar, electron-donating substituents.

Application

4-Methoxybenzamide serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and peptide mimetics. Its amide functionality offers enhanced metabolic stability and improved solubility compared to unsubstituted analogs. The para-methoxy group provides favorable electronic modulation and facilitates ortho-functionalization in subsequent synthetic steps. This compound exhibits excellent bench stability, ease of purification, and compatibility with standard coupling reactions, making it well-suited for iterative synthesis campaigns in API development.

Synthesis

  • Route1
    • 4-Methoxybenzaldehyde, ≥ 99% GC|CS-0676496
      123-11-5
    • ~95%
    • In-stock
      4-Methoxybenzamide|CS-W022205
      3424-93-9

    References

    • Ganguly, Nemai C.; Roy, Sushmita; Mondal, Pallab Tetrahedron Letters, 2012 , vol. 53, # 11 p. 1413 - 1416
  • Route2
    • null|null
      201230-82-2
    • In-stock
      4-Iodoanisole|CS-W003965
      696-62-8
    • ~94%
    • In-stock
      4-Methoxybenzamide|CS-W022205
      3424-93-9

    References

    • Xu, Tongyu; Alper, Howard Tetrahedron Letters, 2013 , vol. 54, # 40 p. 5496 - 5499
  • Route3

    References

    • Ramon, Ruben S.; Bosson, Johann; Diez-Gonzalez, Silvia; Marion, Nicolas; Nolan, Steven P. Journal of Organic Chemistry, 2010 , vol. 75, # 4 p. 1197 - 1202

Safety Information

Download SDS
GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.7941
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Methoxybenzamide sigma4-Methoxybenzamide manufacturer4-Methoxybenzamide price4-Methoxybenzamide structure4-Methoxybenzamide SDSbuy 4-Methoxybenzamide4-Methoxybenzamide supplier4-Methoxybenzamide uses4-Methoxybenzamide molecular weightprice of 4-Methoxybenzamide4-Methoxybenzamide chemical name formula of 4-Methoxybenzamide
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label