Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-(2-Fluoro-3-nitrophenyl)ethanone

  • CAS No. 873697-78-0

  • Cat. No. CS-0042563
  • Molecule weight183.14
  • Purity≥98%
  • MDL No.MFCD13194361

*For research and further manufacturing use only, not for direct human use.

1-(2-Fluoro-3-nitrophenyl)ethanone|CS-0042563

Structure of 873697-78-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 873697-78-0
  • Cat. No. CS-0042563
  • Purity ≥98%
  • MDL No. MFCD13194361
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆FNO₃
  • Molecular Weight 183.14
  • Synonym(s) 2'-fluoro-3'-nitroacetophenone
  • SMILES CC(C1=CC=CC([N+]([O-])=O)=C1F)=O

Description

1-(2-Fluoro-3-nitrophenyl)ethanone features a fluorinated aromatic ring paired with a nitro group in the ortho position relative to the ketone, delivering enhanced electrophilicity and stability under standard conditions. This arrangement facilitates efficient coupling reactions in synthetic organic chemistry, particularly in the construction of complex heterocycles and pharmaceutical intermediates.

Application

1-(2-Fluoro-3-nitrophenyl)ethanone serves as a versatile building block in medicinal chemistry, enabling efficient construction of fused heterocycles and substituted aryl scaffolds. Its ortho-fluoro and meta-nitro substituents provide orthogonal reactivity for palladium-catalyzed cross-coupling and selective reduction sequences. The ketone functionality facilitates nucleophilic additions and enolization, while the compound exhibits sufficient bench stability for routine handling and purification.

Synthesis

  • Route1
    • null|null
      943769-01-5
    • ~%
    • In-stock
      1-(2-Fluoro-3-nitrophenyl)ethanone|CS-0042563
      873697-78-0

    References

    • Morgan, Bradley Paul; Muci, Alex; Lu, Pu-Ping; Kraynack, Erica Anne; Tochimoto, Todd; Morgans, David J. Patent: US2006/14761 A1, 2006 ; Location in patent: Page/Page column 36 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   60.21
  • LogP   1.9365
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-(2-Fluoro-3-nitrophenyl)ethanone sigma1-(2-Fluoro-3-nitrophenyl)ethanone manufacturer1-(2-Fluoro-3-nitrophenyl)ethanone price1-(2-Fluoro-3-nitrophenyl)ethanone structure1-(2-Fluoro-3-nitrophenyl)ethanone SDSbuy 1-(2-Fluoro-3-nitrophenyl)ethanone1-(2-Fluoro-3-nitrophenyl)ethanone supplier1-(2-Fluoro-3-nitrophenyl)ethanone uses1-(2-Fluoro-3-nitrophenyl)ethanone molecular weightprice of 1-(2-Fluoro-3-nitrophenyl)ethanone1-(2-Fluoro-3-nitrophenyl)ethanone chemical name formula of 1-(2-Fluoro-3-nitrophenyl)ethanone
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label