Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-1H-indol-6-amine

  • CAS No. 873055-33-5

  • Cat. No. CS-0043008
  • Purity≥97%
  • MDL No.MFCD09880057

*For research and further manufacturing use only, not for direct human use.

5-Bromo-1H-indol-6-amine|CS-0043008

Structure of 873055-33-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 873055-33-5
  • Cat. No. CS-0043008
  • Purity ≥97%
  • MDL No. MFCD09880057
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇BrN₂
  • Molecular Weight 211.06
  • Synonym(s) 6-Amino-5-bromoindole
  • SMILES NC1=CC2=C(C=CN2)C=C1Br

Description

5-Bromo-1H-indol-6-amine features a bromine substituent at the 5-position and a primary amine at the 6-position of the indole core. This configuration enables direct incorporation into Suzuki-Miyaura couplings and other cross-coupling reactions, facilitating rapid access to functionalized indole derivatives for medicinal chemistry and materials science applications.

Application

5-Bromo-1H-indol-6-amine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the 6-position via palladium-catalyzed cross-coupling reactions. Its bromo group exhibits high reactivity in Suzuki, Stille, and Negishi transformations, while the pendant amine facilitates conjugation or derivatization under mild conditions. The molecule demonstrates excellent bench stability and is readily purified by standard chromatographic methods, making it well-suited for scalable synthesis of indole-based pharmaceuticals and kinase inhibitors.

Synthesis

  • Route1

    References

    • US2011/98311 A1, ;
  • Route2

    References

    • US2011/98311 A1, ;
  • Route3

    References

    • US2011/98311 A1, ; US2012/309758 A1, ; US 20120309758 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   41.81
  • LogP   2.5126
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Bromo-1H-indol-6-amine sigma5-Bromo-1H-indol-6-amine manufacturer5-Bromo-1H-indol-6-amine price5-Bromo-1H-indol-6-amine structure5-Bromo-1H-indol-6-amine SDSbuy 5-Bromo-1H-indol-6-amine5-Bromo-1H-indol-6-amine supplier5-Bromo-1H-indol-6-amine uses5-Bromo-1H-indol-6-amine molecular weightprice of 5-Bromo-1H-indol-6-amine5-Bromo-1H-indol-6-amine chemical name formula of 5-Bromo-1H-indol-6-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label