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CS-W001157 4
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4-Bromo-1H-indol-6-amine

  • CAS No. 375369-03-2

  • Cat. No. CS-0089461
  • Molecule weight211.06
  • Purity≥95%
  • MDL No.MFCD03095014

*For research and further manufacturing use only, not for direct human use.

4-Bromo-1H-indol-6-amine|CS-0089461

Structure of 375369-03-2

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General Information

  • CAS No. 375369-03-2
  • Cat. No. CS-0089461
  • Purity ≥95%
  • MDL No. MFCD03095014
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇BrN₂
  • Molecular Weight 211.06
  • Synonym(s) 4-BROMO-6-AMINOINDOLE
  • SMILES NC1=CC2=C(C(Br)=C1)C=CN2

Description

4-Bromo-1H-indol-6-amine features a brominated indole core with a primary amine at the C6 position, enabling direct incorporation into diverse heterocyclic scaffolds. This electron-rich scaffold supports efficient coupling reactions and serves as a key building block in medicinal chemistry for bioactive molecule synthesis.

Application

4-Bromo-1H-indol-6-amine serves as a versatile building block for the synthesis of biologically active indole derivatives. Its bromine and primary amine functionalities enable efficient cross-coupling reactions and derivatization, facilitating access to diverse heterocyclic scaffolds. The compound exhibits good bench stability and compatibility with standard purification methods, making it suitable for medicinal chemistry campaigns and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.81
  • LogP   2.5126
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   0

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