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CS-W001157 4
Total: USD 88.00

4-Amino-2,6-dihydroxypyrimidine Tofacitinib Impurity

  • CAS No. 873-83-6

  • Cat. No. CS-0229350
  • Purity≥98%
  • MDL No.MFCD00006071

*For research and further manufacturing use only, not for direct human use.

4-Amino-2,6-dihydroxypyrimidine Tofacitinib  Impurity|CS-0229350

Structure of 873-83-6

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General Information

  • CAS No. 873-83-6
  • Cat. No. CS-0229350
  • Purity ≥98%
  • MDL No. MFCD00006071
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅N₃O₂
  • Molecular Weight 127.10
  • Synonym(s) 6-Aminouracil
  • SMILES OC1=CC(N)=NC(O)=N1

Synthesis

  • Route1

    References

    • Sariri; Khalili Russian Journal of Organic Chemistry, 2002 , vol. 38, # 7 p. 1053 - 1055
  • Route2
    • N-Carbamoyl-2-cyanoacetamide|CS-W013487
      1448-98-2
    • ~%
    • 4-Amino-2,6-dihydroxypyrimidine Tofacitinib  Impurity|CS-0229350
      873-83-6

    References

    • DE117922 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 6, p. 1189 Chemische Berichte, , vol. 33, p. 1381,3044 Chem. Zentralbl., , vol. 72, # I p. 547
  • Route3

    References

    • Katori; Nagano; Kunieda; Hirobe Chemical and pharmaceutical bulletin, 1981 , vol. 29, # 10 p. 3075 - 3077

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   92.26
  • LogP   -0.53
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   0

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