2,4-Dibromoquinazoline

Name: 2,4-Dibromoquinazoline
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 872998-61-3
Cat. No. CS-0019340
Purity≥95%
MDL No.MFCD09909697

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 872998-61-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 872998-61-3
Cat. No. CS-0019340
Purity ≥95%
MDL No. MFCD09909697
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₄Br₂N₂
Molecular Weight None
Synonym(s) None
SMILES BrC1=C2C=CC=CC2=NC(Br)=N1

Description

2,4-Dibromoquinazoline serves as a key building block in medicinal chemistry, featuring two bromine substituents at electron-rich positions that enable efficient palladium-catalyzed cross-coupling reactions. This stable, bench-ready heterocycle integrates readily into complex scaffolds for kinase inhibitor development and functional materials synthesis.

Application

2,4-Dibromoquinazoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biaryl and heterocyclic scaffolds. The dibromo substitution pattern provides high reactivity in Suzuki, Stille, and Negishi couplings, facilitating rapid diversification of quinazoline cores. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for iterative synthesis campaigns targeting kinase inhibitors and other bioactive molecules.

Synthesis

Route1
- In-stock
  
  86-96-4
- ~50%
- In-stock
  
  872998-61-3
References
- Tangirala, Raghuraman; Antony, Smitha; Agama, Keli; Pommier, Yves; Curran, Dennis P. Synlett, 2005 , # 18 art. no. Y06205ST, p. 2843 - 2846

Safety Information

Download SDS

GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 25.78
LogP 3.1548
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Quinazoline compounds

Key Words

2,4-Dibromoquinazoline sigma2,4-Dibromoquinazoline manufacturer2,4-Dibromoquinazoline price2,4-Dibromoquinazoline structure2,4-Dibromoquinazoline SDSbuy 2,4-Dibromoquinazoline2,4-Dibromoquinazoline supplier2,4-Dibromoquinazoline uses2,4-Dibromoquinazoline molecular weightprice of 2,4-Dibromoquinazoline2,4-Dibromoquinazoline chemical name formula of 2,4-Dibromoquinazoline

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2,4-Dibromoquinazoline

CAS No. 872998-61-3

Recommended Products