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CS-W001157 4
Total: USD 88.00

6-Bromo-3-fluoro-2-nitrophenol

  • CAS No. 872363-59-2

  • Cat. No. CS-0157205
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD23701729

*For research and further manufacturing use only, not for direct human use.

6-Bromo-3-fluoro-2-nitrophenol|CS-0157205

Structure of 872363-59-2

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General Information

  • CAS No. 872363-59-2
  • Cat. No. CS-0157205
  • Purity ≥97%
  • MDL No. MFCD23701729
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrFNO₃
  • Molecular Weight None
  • Synonym(s) None
  • SMILES C1=CC(=C(C(=C1Br)O)[N+](=O)[O-])F

Description

6-Bromo-3-fluoro-2-nitrophenol features a strategically positioned bromine, fluorine, and nitro group on the phenolic ring, enabling selective functionalization in complex synthesis. The electron-withdrawing nitro and halogen substituents enhance reactivity in cross-coupling and nucleophilic substitution processes. This bench-stable compound serves as a key intermediate for advanced pharmaceuticals and agrochemicals.

Application

6-Bromo-3-fluoro-2-nitrophenol serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its strategic placement of bromo, fluoro, and nitro groups enables sequential cross-coupling, nucleophilic substitution, and reduction reactions under standard conditions. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H312-H332-H318-H315-H335
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P310-P312-P330-P332+P313-P362+P364-P363-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.37
  • LogP   2.202
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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