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CS-W001157 4
Total: USD 88.00

5-Bromo-3-isopropyl-1H-indole

  • CAS No. 439612-51-8

  • Cat. No. CS-0158987
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-isopropyl-1H-indole|CS-0158987

Structure of 439612-51-8

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General Information

  • CAS No. 439612-51-8
  • Cat. No. CS-0158987
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂BrN
  • Molecular Weight 238.12
  • Synonym(s) None
  • SMILES CC(C1=CNC2=C1C=C(Br)C=C2)C

Description

5-Bromo-3-isopropyl-1H-indole is a brominated indole derivative featuring a sterically hindered isopropyl group at the 3-position, enhancing stability and modulating electronic properties. This scaffold integrates readily into bioactive molecules, serving as a key intermediate in medicinal chemistry for targeted synthesis of heterocyclic compounds with defined spatial and electronic profiles.

Application

5-Bromo-3-isopropyl-1H-indole serves as a versatile building block in the synthesis of biologically active heterocycles and pharmaceutical intermediates. Its well-defined reactivity enables palladium-catalyzed cross-coupling reactions, facilitating the construction of complex indole-based scaffolds with high functional group tolerance and excellent bench stability.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   15.79
  • LogP   4.0538
  • H_Acceptors   0
  • H_Donors   1
  • Rotatable_Bonds   1

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