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CS-W001157 4
Total: USD 88.00

4-Amino-2,5-dibromophenol

  • CAS No. 872272-33-8

  • Cat. No. CS-0157835
  • Purity≥98%
  • MDL No.MFCD28040627

*For research and further manufacturing use only, not for direct human use.

4-Amino-2,5-dibromophenol|CS-0157835

Structure of 872272-33-8

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General Information

  • CAS No. 872272-33-8
  • Cat. No. CS-0157835
  • Purity ≥98%
  • MDL No. MFCD28040627
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅Br₂NO
  • Molecular Weight 266.92
  • Synonym(s) 4-Amino-2,5-dibrom-phenol
  • SMILES C1=C(C(=CC(=C1N)Br)O)Br

Description

4-Amino-2,5-dibromophenol features a phenolic hydroxyl group flanked by two bromine substituents and an amino moiety at the para position. This electron-rich scaffold enables direct coupling in cross-coupling reactions and serves as a building block for functionalized aryl derivatives. The molecule exhibits enhanced reactivity due to the synergistic influence of the amino and bromo groups.

Application

4-Amino-2,5-dibromophenol serves as a versatile building block for brominated aromatic scaffolds in medicinal chemistry and materials science. Its dual bromine substituents enable selective cross-coupling reactions, while the phenolic hydroxyl and primary amine groups offer orthogonal functionalization handles. The compound exhibits good bench stability and facilitates efficient derivatization under standard coupling conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   2.4994
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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