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Structure of 872091-92-4
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This cyanopropanyl isonicotinic acid features a sterically hindered nitrile group flanking a pyridine ring, enabling robust conjugation and enhanced metabolic stability. The para-positioned carboxylic acid facilitates direct coupling to biomolecules or resins under standard conditions, while the electron-deficient pyridine core supports selective reactivity in transition-metal-catalyzed transformations.
2-(2-Cyanopropan-2-yl)isonicotinic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized pyridine scaffolds. Its tertiary nitrile group provides robust stability and facilitates downstream transformations such as hydrolysis or nucleophilic addition. The molecule exhibits excellent bench stability, clean reaction profiles, and compatibility with standard coupling protocols, making it well-suited for parallel synthesis and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: