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CS-W001157 4
Total: USD 88.00

2-(Hydroxymethyl)phenylboronic acid

  • CAS No. 87199-14-2

  • Cat. No. CS-W000996
  • Purity≥98%
  • MDL No.MFCD02258966

*For research and further manufacturing use only, not for direct human use.

2-(Hydroxymethyl)phenylboronic acid|CS-W000996

Structure of 87199-14-2

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General Information

  • CAS No. 87199-14-2
  • Cat. No. CS-W000996
  • Purity ≥98%
  • MDL No. MFCD02258966
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉BO₃
  • Molecular Weight 151.96
  • Synonym(s) O-(HYDROXYMETHYL)PHENYLBORONIC ACID; 2-(Hydroxymethyl)phenylboronic acid
  • SMILES OCc1ccccc1B(O)O

Description

2-Bromo-4'-(diethylamino)acetophenone, is used as non-ionic dialyzable detergent.

Application

2-(Hydroxymethyl)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of biaryl and heteroaryl architectures. The ortho-hydroxymethyl group provides additional functionality for downstream derivatization, while the boronic acid moiety offers excellent bench stability and compatibility with diverse reaction conditions. Its defined regiochemistry and predictable reactivity make it a reliable choice for synthesizing complex aromatic scaffolds in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • null|null
      932-31-0
    • ~%
    • In-stock
      2-(Hydroxymethyl)phenylboronic acid|CS-W000996
      87199-14-2

    References

    • B: B-Verb.13, 4.7.2.5, page 209 - 219
  • Route2
    • null|null
      7294-50-0
    • ~%
    • In-stock
      2-(Hydroxymethyl)phenylboronic acid|CS-W000996
      87199-14-2

    References

    • B: B-Verb.13, 4.7.2.5, page 209 - 219
  • Route3
    • null|null
      7481-16-5
    • null|null
      7732-18-5
    • ~%
    • In-stock
      2-(Hydroxymethyl)phenylboronic acid|CS-W000996
      87199-14-2

    References

    • Arkiv foer Kemi, , vol. 10, p. 507 - 511

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   60.69
  • LogP   -1.1413
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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