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CS-W001157 4
Total: USD 88.00

Boronic acid, [4-(cyclopropyloxy)phenyl]-

  • CAS No. 871829-90-2

  • Cat. No. CS-0030605
  • Purity≥98%
  • MDL No.None
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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

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*For research and further manufacturing use only, not for direct human use.

Boronic acid, [4-(cyclopropyloxy)phenyl]-|CS-0030605

Structure of 871829-90-2

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Description

This boronate moiety integrates a cyclopropoxy substituent at the para position, enhancing solubility and stability in aqueous-organic media. The electron-deficient arylboronic acid facilitates efficient Suzuki-Miyaura coupling under mild conditions, enabling rapid assembly of complex biaryl architectures in medicinal chemistry and materials synthesis.

Application

(4-Cyclopropoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its cyclopropoxy substituent imparts favorable electronic properties and enhanced stability compared to more labile aryl boronates. The compound exhibits excellent bench stability, tolerates common functional groups, and facilitates straightforward purification—making it ideal for constructing complex heterocycles and biaryl scaffolds in medicinal chemistry and materials synthesis.

General Information

  • CAS No. 871829-90-2
  • Cat. No. CS-0030605
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BO₃
  • Molecular Weight 177.99
  • Synonym(s) 4-Cyclopropoxyphenylboronic acid
  • SMILES OB(C1=CC=C(OC2CC2)C=C1)O

Computational Chemistry Data

  • TPSA   49.69
  • LogP   -0.0924
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P261-P280-P304+P340-P405

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