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tert-Butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate

  • CAS No. 871726-73-7

  • Cat. No. CS-B1004
  • Purity≥97%
  • MDL No.MFCD11044813

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate|CS-B1004

Structure of 871726-73-7

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General Information

  • CAS No. 871726-73-7
  • Cat. No. CS-B1004
  • Purity ≥97%
  • MDL No. MFCD11044813
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇N₃O₂
  • Molecular Weight 223.27
  • Synonym(s) None
  • SMILES O=C(N1CCC2=C(NN=C2)C1)OC(C)(C)C

Description

tert-Butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate features a rigid, electron-rich heterocyclic core with a bench-stable tert-butyl ester handle, enabling direct incorporation into medicinal chemistry campaigns. This scaffold delivers structural diversity in CNS-targeted lead discovery and serves as a versatile intermediate for pyrazolopyridine-based kinase inhibitors.

Application

tert-Butyl 4,5-dihydro-1H-pyrazolo[3,4-c]pyridine-6(7H)-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and synthetic methodology development. The dihydropyrazolopyridine core enables efficient functionalization at the C6 position and supports transition-metal-catalyzed coupling reactions. Its tert-butyl ester group provides bench stability and facilitates straightforward deprotection under mild acidic conditions, enhancing utility in multi-step synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.22
  • LogP   1.7029
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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