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CS-W001157 4
Total: USD 88.00

(3-Carbamoyl-5-fluorophenyl)boronic acid

  • CAS No. 871332-66-0

  • Cat. No. CS-W017073
  • Purity≥98%
  • MDL No.MFCD08056357

*For research and further manufacturing use only, not for direct human use.

(3-Carbamoyl-5-fluorophenyl)boronic acid|CS-W017073

Structure of 871332-66-0

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General Information

  • CAS No. 871332-66-0
  • Cat. No. CS-W017073
  • Purity ≥98%
  • MDL No. MFCD08056357
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇BFNO₃
  • Molecular Weight 182.94
  • Synonym(s) 3-CARBAMOYL-5-FLUOROPHENYLBORONIC ACID
  • SMILES FC1=CC(C(N)=O)=CC(B(O)O)=C1

Description

This boronic acid features a carbamoyl group ortho to a fluorinated phenyl ring, enhancing solubility and stability. The electron-deficient aryl moiety enables efficient Suzuki-Miyaura coupling under standard conditions. Designed for synthetic precision in medicinal chemistry and materials science applications.

Application

(3-Carbamoyl-5-fluorophenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures under mild conditions. The ortho-fluorine and carbamoyl groups provide enhanced stability and modulate electronic properties, facilitating downstream functionalization. Its bench-stable nature and compatibility with diverse reaction partners make it well-suited for medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   83.55
  • LogP   -1.3956
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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