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CS-W001157 4
Total: USD 88.00

(6-Chloronaphthalen-2-yl)boronic acid

  • CAS No. 870822-86-9

  • Cat. No. CS-0539693
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(6-Chloronaphthalen-2-yl)boronic acid|CS-0539693

Structure of 870822-86-9

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General Information

  • CAS No. 870822-86-9
  • Cat. No. CS-0539693
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BClO₂
  • Molecular Weight 206.43
  • Synonym(s) (6-Chloro-2-naphthyl)boronic acid
  • SMILES B(C1=CC2=C(C=C1)C=C(C=C2)Cl)(O)O

Description

(6-Chloronaphthalen-2-yl)boronic acid features a chlorinated naphthalene scaffold bearing a boronic acid group at the 6-position, enabling efficient Suzuki-Miyaura cross-coupling reactions. This bench-stable reagent integrates readily into complex molecular architectures, offering predictable regioselectivity and compatibility with diverse reaction conditions.

Application

(6-Chloronaphthalen-2-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation with aryl and heteroaryl halides. The chloro substituent provides orthogonal reactivity for downstream functionalization, while the boronic acid moiety offers excellent bench stability and compatibility with diverse reaction conditions. Its utility in constructing biaryl scaffolds makes it a reliable reagent for pharmaceutical and materials chemistry applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.173
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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