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Structure of 870704-22-6
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This pyrazole carboxylic acid integrates a 4-fluorophenyl group at the 3-position, delivering enhanced electron-withdrawing character and improved metabolic stability. The carboxylic acid functionality enables direct coupling or salt formation, supporting downstream derivatization in medicinal chemistry campaigns.
3-(4-Fluorophenyl)-1H-pyrazole-5-carboxylic acid serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, offering a well-defined scaffold for drug discovery programs. Its carboxylic acid functionality enables direct derivatization via amide coupling, esterification, or metal-catalyzed transformations. The 4-fluorophenyl substituent enhances metabolic stability and modulates electronic properties, while the pyrazole core provides favorable hydrogen-bonding capacity and planar geometry. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: