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CS-W001157 4
Total: USD 88.00

tert-Butyl carbazate

  • CAS No. 870-46-2

  • Cat. No. CS-W008846
  • Purity≥97%
  • MDL No.MFCD00007593

*For research and further manufacturing use only, not for direct human use.

tert-Butyl carbazate|CS-W008846

Structure of 870-46-2

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General Information

  • CAS No. 870-46-2
  • Cat. No. CS-W008846
  • Purity ≥97%
  • MDL No. MFCD00007593
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂N₂O₂
  • Molecular Weight 132.16
  • Synonym(s) None
  • SMILES NNC(OC(C)(C)C)=O

Description

t-Boc-Aminooxy-PEG4-Tos is a bifunctional crosslinker reagent with a t-Boc-aminooxy group and a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution. The protected aminooxy can be deprotected under mild acidic conditions. PEG5 spacer increases solubility in aqueous media.

Synthesis

  • Route1

    References

    • Wang, Ziwen; Wang, Mingxiao; Yao, Xue; Li, Yue; Tan, Juan; Wang, Lizhong; Qiao, Wentao; Geng, Yunqi; Liu, Yuxiu; Wang, Qingmin European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 33 - 41
  • Route2

    References

    • Yamamoto, Yoshinori; Yumoto, Masatoshi; Yamada, Jun-ichi Tetrahedron Letters, 1991 , vol. 32, # 26 p. 3079 - 3082
  • Route3
    • null|null
      1860-21-5
    • ~%
    • In-stock
      tert-Butyl carbazate|CS-W008846
      870-46-2

    References

    • Journal of the American Chemical Society, , vol. 82, p. 2725 - 2727

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅱ
Hazard Statements : H228-H302-H315-H319-H335
Precautionary Statements : P210-P240-P241-P280-P370+P378

Quality Control

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   0.3848
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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