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CS-W001157 4
Total: USD 88.00

(1-Methyl-1H-pyrazol-3-yl)boronic acid

  • CAS No. 869973-96-6

  • Cat. No. CS-0108755
  • Purity≥97%
  • MDL No.MFCD11977279

*For research and further manufacturing use only, not for direct human use.

(1-Methyl-1H-pyrazol-3-yl)boronic acid|CS-0108755

Structure of 869973-96-6

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General Information

  • CAS No. 869973-96-6
  • Cat. No. CS-0108755
  • Purity ≥97%
  • MDL No. MFCD11977279
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇BN₂O₂
  • Molecular Weight 125.92
  • Synonym(s) BORONIC ACID, B-(1-METHYL-1H-PYRAZOL-3-YL)-
  • SMILES OB(C1=NN(C)C=C1)O

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering functionalized heterocycles with high efficiency. The pyrazole scaffold enhances solubility and stability in aqueous media, enabling robust performance across diverse reaction matrices.

Application

(1-Methyl-1H-pyrazol-3-yl)boronic acid serves as a stable, bench-ready boron source for Suzuki-Miyaura cross-coupling reactions. It exhibits excellent functional group tolerance and facilitates efficient C–C bond formation with aryl and heteroaryl halides. The pyrazole moiety enhances solubility and stability, enabling straightforward purification and integration into complex molecular architectures common in medicinal chemistry and agrochemical research.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   58.28
  • LogP   -1.9001
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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