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CS-W001157 4
Total: USD 88.00

N-tert-Butoxycarbonyl-D-alanine

  • CAS No. 7764-95-6

  • Cat. No. CS-D1467
  • Purity≥98%
  • MDL No.MFCD00063123

*For research and further manufacturing use only, not for direct human use.

N-tert-Butoxycarbonyl-D-alanine|CS-D1467

Structure of 7764-95-6

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General Information

  • CAS No. 7764-95-6
  • Cat. No. CS-D1467
  • Purity ≥98%
  • MDL No. MFCD00063123
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅NO₄
  • Molecular Weight None
  • Synonym(s) None
  • SMILES C[C@H](C(O)=O)NC(OC(C)(C)C)=O

Description

N-tert-Butoxycarbonyl-D-alanine delivers a protected D-alanine scaffold with enhanced stability and ease of handling. The tert-butoxycarbonyl group enables selective deprotection under mild acidic conditions, facilitating efficient incorporation into peptide sequences. This derivative serves as a key intermediate in the synthesis of non-natural amino acid-containing peptides and peptidomimetics.

Application

N-tert-Butoxycarbonyl-D-alanine serves as a stable, bench-ready building block for peptide synthesis, enabling efficient N-terminal protection of D-alanine residues. Its tert-butoxycarbonyl (Boc) group offers excellent stability under basic conditions and facilitates orthogonal deprotection in multi-step sequences. The molecule exhibits high functional group tolerance and simplifies purification due to its crystalline nature, making it ideal for solid-phase and solution-phase peptide assembly workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   0.9842
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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