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2-Amino-5-bromopyridine-3-sulfonyl chloride

  • CAS No. 868963-98-8

  • Cat. No. CS-0261525
  • Molecule weight271.52
  • Purity≥97%
  • MDL No.MFCD16619350

*For research and further manufacturing use only, not for direct human use.

2-Amino-5-bromopyridine-3-sulfonyl chloride|CS-0261525

Structure of 868963-98-8

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General Information

  • CAS No. 868963-98-8
  • Cat. No. CS-0261525
  • Purity ≥97%
  • MDL No. MFCD16619350
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄BrClN₂O₂S
  • Molecular Weight 271.52
  • Synonym(s) 2-amino-5-bromo-3-pyridinesulfonyl chloride
  • SMILES C1=C(C=NC(=C1S(=O)(=O)Cl)N)Br

Synthesis

  • Route1

    References

    • SMITHKLINE BEECHAM CORPORATION Patent: WO2008/157191 A2, 2008 ; Location in patent: Page/Page column 74 ; WO 2008/157191 A2
  • Route2
    • In-stock
      2-Amino-5-bromopyridine|CS-D1666
      1072-97-5
    • null|null
      7790-94-5
    • ~%
    • In-stock
      2-Amino-5-bromopyridine-3-sulfonyl chloride|CS-0261525
      868963-98-8

    References

    • PETER MACCALLUM CANCER INSTITUTE; SPICER, Julie Ann; DENNY, William Alexander; MILLER, Christian Karl; O'CONNOR, Patrick David; HUTTUNEN, Kristiina; TRAPANI, Joseph A.; HILL, Geoff; ALEXANDER, Kylie Patent: WO2014/28968 A1, 2014 ; Location in patent: Page/Page column 98 ;
  • Route3

    References

    • Leahy, James W.; Buhr, Chris A.; Johnson, Henry W. B.; Kim, Byung Gyu; Baik, Taegon; Cannoy, Jonah; Forsyth, Timothy P.; Jeong, Joon Won; Lee, Matthew S.; Ma, Sunghoon; Noson, Kevin; Wang, Longcheng; Williams, Matthew; Nuss, John M.; Brooks, Eric; Foster, Paul; Goon, Leanne; Heald, Nathan; Holst, Charles; Jaeger, Christopher; Lam, Scott; Lougheed, Julie; Nguyen, Lam; Plonowski, Arthur; Song, Joanne; Stout, Thomas; Wu, Xiang; Yakes, Michael F.; Yu, Peiwen; Zhang, Wentao; Lamb, Peter; Raeber, Olivia Journal of Medicinal Chemistry, 2012 , vol. 55, # 11 p. 5467 - 5482

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H312-H314-H332-H335
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P301+P330+P331-P302+P352-P303+P361+P353-P304+P341-P304+P340-P305+P351+P338-P310-P312-P330-P363-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   73.05
  • LogP   1.3538
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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