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CS-W001157 4
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6-Amino-3-pyridinesulfonyl chloride

  • CAS No. 289483-92-7

  • Cat. No. CS-0199562
  • Molecule weight192.62
  • Purity≥98%
  • MDL No.MFCD18254623

*For research and further manufacturing use only, not for direct human use.

6-Amino-3-pyridinesulfonyl chloride|CS-0199562

Structure of 289483-92-7

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General Information

  • CAS No. 289483-92-7
  • Cat. No. CS-0199562
  • Purity ≥98%
  • MDL No. MFCD18254623
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅ClN₂O₂S
  • Molecular Weight 192.62
  • Synonym(s) 6-Aminopyridine-3-sulfonyl chloride
  • SMILES O=S(=O)(Cl)C1=CN=C(N)C=C1

Synthesis

  • Route1
    • null|null
      504-29-0
    • ~35%
    • 6-Amino-3-pyridinesulfonyl chloride|CS-0199562
      289483-92-7

    References

    • Prime, Michael E.; Andersen, Ole A.; Barker, John J.; Brooks, Mark A.; Cheng, Robert K. Y.; Toogood-Johnson, Ian; Courtney, Stephen M.; Brookfield, Frederick A.; Yarnold, Christopher J.; Marston, Richard W.; Johnson, Peter D.; Johnsen, Siw F.; Palfrey, Jordan J.; Vaidya, Darshan; Erfan, Sayeh; Ichihara, Osamu; Felicetti, Brunella; Palan, Shilpa; Pedret-Dunn, Anna; Schaertl, Sabine; Sternberger, Ina; Ebneth, Andreas; Scheel, Andreas; Winkler, Dirk; Toledo-Sherman, Leticia; Beconi, Maria; MacDonald, Douglas; Munoz-Sanjuan, Ignacio; Dominguez, Celia; Wityak, John Journal of Medicinal Chemistry, 2012 , vol. 55, # 3 p. 1021 - 1046
  • Route2
    • null|null
      504-29-0
    • ~%
    • 6-Amino-3-pyridinesulfonyl chloride|CS-0199562
      289483-92-7
    • null|null
      70661-77-7

    References

    • AMGEN INC.; ASHTON, Kate; BARTBERGER, Michael David; BO, Yunxin; BRYAN, Marian C.; CROGHAN, Michael; FOTSCH, Christopher Harold; HALE, Clarence Henderson; KUNZ, Roxanne Kay; LIU, Longbin; NISHIMURA, Nobuko; NORMAN, Mark H.; PENNINGTON, Lewis Dale; POON, Steve Fong; STEC, Markian Myroslaw; ST. JEAN, David, Joseph, Jr.; TAMAYO, Nuria A.; TEGLEY, Christopher Michael; YANG, Kevin Chao Patent: WO2012/27261 A1, 2012 ; Location in patent: Page/Page column 498-500 ; WO 2012/027261 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501

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Computational Chemistry Data

  • TPSA   73.05
  • LogP   0.5913
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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