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CS-W001157 4
Total: USD 88.00

1-Propanamine, 2,2-difluoro-, hydrochloride

  • CAS No. 868241-48-9

  • Cat. No. CS-0028374
  • Purity≥96%
  • MDL No.MFCD06659051
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Propanamine, 2,2-difluoro-, hydrochloride|CS-0028374

Structure of 868241-48-9

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Description

2,2-Difluoropropylamine hydrochloride is a bench-stable, moisture-tolerant amine derivative featuring a geminal difluoro substitution that imparts enhanced metabolic stability. This fluorinated alkylamine integrates readily into bioactive molecules, serving as a key building block for pharmaceutical intermediates and functionalized polymers where lipophilicity and resistance to oxidative degradation are critical.

Application

2,2-Difluoropropylamine hydrochloride serves as a valuable building block for fluorinated bioactive molecules, enabling the introduction of a stable, lipophilic difluoromethyl group into pharmaceutical and agrochemical scaffolds. Its bench-stable nature and compatibility with standard amine functionalization protocols facilitate efficient synthesis of target compounds via nucleophilic substitution or reductive amination.

General Information

  • CAS No. 868241-48-9
  • Cat. No. CS-0028374
  • Purity ≥96%
  • MDL No. MFCD06659051
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₈ClF₂N
  • Molecular Weight 131.55
  • Synonym(s) 2,2-DIFLUOROPROPAN-1-AMINE HCL
  • SMILES NCC(F)(F)C.[H]Cl

Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.0221
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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