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Structure of 866363-70-4
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N3-C5-NHS ester is a bifunctional crosslinker featuring a reactive NHS ester and an azide group separated by a five-atom aliphatic spacer. This design enables site-specific conjugation via copper-free click chemistry, facilitating efficient bioconjugation under physiological conditions. The spacer enhances solubility and reduces steric interference during labeling.
N3-C5-NHS ester serves as a versatile, bench-stable linker for site-specific conjugation in synthetic chemistry. Its NHS ester moiety enables efficient coupling to primary amines under physiological conditions, while the azide group facilitates orthogonal click reactions with triarylphosphine or strained alkyne partners. This bifunctional reagent simplifies the construction of bioconjugates and functionalized scaffolds in medicinal chemistry and materials science workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: