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CS-W001157 4
Total: USD 88.00

2, 5-Dioxo-1-pyrrolidinyl 11-azidoundecanoate

  • CAS No. 850080-13-6

  • Cat. No. CS-0254627
  • Purity≥95%
  • MDL No.MFCD29041759

*For research and further manufacturing use only, not for direct human use.

2, 5-Dioxo-1-pyrrolidinyl 11-azidoundecanoate|CS-0254627

Structure of 850080-13-6

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General Information

  • CAS No. 850080-13-6
  • Cat. No. CS-0254627
  • Purity ≥95%
  • MDL No. MFCD29041759
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₄N₄O₄
  • Molecular Weight 324.38
  • Synonym(s) None
  • SMILES [N-]=[N+]=NCCCCCCCCCCC(ON1C(CCC1=O)=O)=O

Description

This azide-functionalized ester integrates a pyrrolidinone core with a long aliphatic chain, enabling site-specific conjugation in bioorthogonal labeling. The 11-azidoundecanoate moiety delivers enhanced solubility and stability under standard conditions, while the dioxopyrrolidine ring provides controlled reactivity. Designed for efficient coupling in peptide and polymer modification workflows.

Application

2,5-Dioxo-1-pyrrolidinyl 11-azidoundecanoate serves as a versatile bifunctional building block for conjugate addition and strain-promoted azide-alkyne cycloaddition (SPAAC) reactions. The pyrrolidinone carbonyl enables efficient Michael addition with nucleophiles, while the terminal azide group facilitates bioorthogonal ligation. Its stability under ambient conditions and compatibility with diverse functional groups make it well-suited for modular synthesis of peptide-protein conjugates and polymer-drug architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   112.44
  • LogP   3.4148
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   12

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