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CS-W001157 4
Total: USD 88.00

(2-Methylbenzo[d]oxazol-6-yl)boronic acid

  • CAS No. 866332-15-2

  • Cat. No. CS-0175869
  • Purity≥96%
  • MDL No.MFCD10697425

*For research and further manufacturing use only, not for direct human use.

(2-Methylbenzo[d]oxazol-6-yl)boronic acid|CS-0175869

Structure of 866332-15-2

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General Information

  • CAS No. 866332-15-2
  • Cat. No. CS-0175869
  • Purity ≥96%
  • MDL No. MFCD10697425
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈BNO₃
  • Molecular Weight None
  • Synonym(s) (2-Methyl-1,3-benzoxazol-6-yl)boronic acid
  • SMILES CC1=NC2=C(O1)C=C(B(O)O)C=C2

Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, delivering high functional group tolerance and stability under standard conditions. The 2-methylbenzo[d]oxazol-6-yl scaffold enhances solubility and electronic modulation, enabling efficient access to complex heteroaryl architectures in medicinal chemistry and materials science applications.

Application

(2-Methylbenzo[d]oxazol-6-yl)boronic acid serves as a robust building block for Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The boronic acid moiety exhibits excellent stability, facilitates straightforward purification, and tolerates a range of functional groups, making it well-suited for constructing complex heterocyclic architectures in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   66.49
  • LogP   -0.18398
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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