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Structure of 865663-99-6
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1-(difluoromethyl)-1H-pyrazol-3-amine features a strategically positioned difluoromethyl group that enhances metabolic stability and membrane permeability. This electron-deficient pyrazole scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for targeted kinase inhibitors and CNS-active compounds.
1-(Difluoromethyl)-1H-pyrazol-3-amine serves as a valuable building block in medicinal chemistry, enabling the introduction of a polar, metabolically stable difluoromethyl group adjacent to a nitrogen-rich heterocyclic core. Its functionality facilitates nucleophilic substitution and coupling reactions, with demonstrated utility in constructing bioactive scaffolds. The compound exhibits good bench stability and compatibility with common reaction conditions, supporting efficient synthesis and purification workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: