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CS-W001157 4
Total: USD 88.00

(4-Chloro-3,5-difluorophenyl)boronic acid

  • CAS No. 864759-63-7

  • Cat. No. CS-0101370
  • Molecule weightNone
  • Purity≥98%
  • MDL No.MFCD08706254

*For research and further manufacturing use only, not for direct human use.

(4-Chloro-3,5-difluorophenyl)boronic acid|CS-0101370

Structure of 864759-63-7

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General Information

  • CAS No. 864759-63-7
  • Cat. No. CS-0101370
  • Purity ≥98%
  • MDL No. MFCD08706254
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄BClF₂O₂
  • Molecular Weight None
  • Synonym(s) Boronicacid, (4-chloro-3,5-difluorophenyl)- (9CI)
  • SMILES FC1=C(C(F)=CC(B(O)O)=C1)Cl

Description

This boronic acid features a trifluorinated aryl core with orthogonal halogen substituents, enabling selective cross-coupling in complex molecule assembly. The 4-chloro and 3,5-difluoro pattern enhances reactivity while maintaining stability under standard conditions.

Application

(4-Chloro-3,5-difluorophenyl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its stability under ambient conditions and compatibility with diverse functional groups facilitate straightforward incorporation into complex molecular architectures, making it a reliable reagent for medicinal chemistry and materials synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.298
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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