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CS-W001157 4
Total: USD 88.00

2-Amino-5-bromo-3-(methyloxy)benzoic acid

  • CAS No. 864293-44-7

  • Cat. No. CS-B1043
  • Purity≥98%
  • MDL No.MFCD11101005
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Amino-5-bromo-3-(methyloxy)benzoic acid|CS-B1043

Structure of 864293-44-7

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Description

This brominated aromatic acid features a methoxy-substituted benzene core with strategically positioned amino and carboxylic acid functionalities. The electron-donating methoxy group enhances solubility and reactivity, while the bromine atom enables facile cross-coupling transformations. Bench-stable under standard conditions, it serves as a key intermediate in the synthesis of bioactive molecules and functional materials.

Application

2-Amino-5-bromo-3-(methyloxy)benzoic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive heterocycles and peptide conjugates. The molecule combines ortho-directed reactivity from the amino and carboxylic acid groups with bromine for cross-coupling applications, while the methoxy group enhances solubility and modulates electronic properties. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient synthesis of complex scaffolds.

General Information

  • CAS No. 864293-44-7
  • Cat. No. CS-B1043
  • Purity ≥98%
  • MDL No. MFCD11101005
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈BrNO₃
  • Molecular Weight 246.06
  • Synonym(s) 2-Amino-5-bromo-3-methoxybenzoic acid
  • SMILES O=C(O)C1=CC(Br)=CC(OC)=C1N

Computational Chemistry Data

  • TPSA   72.55
  • LogP   1.7381
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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