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CS-W001157 4
Total: USD 88.00

Tert-butyl 4-(4-(hydroxymethyl)thiazol-2-yl)piperidine-1-carboxylate

  • CAS No. 864068-79-1

  • Cat. No. CS-0326225
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Tert-butyl 4-(4-(hydroxymethyl)thiazol-2-yl)piperidine-1-carboxylate|CS-0326225

Structure of 864068-79-1

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General Information

  • CAS No. 864068-79-1
  • Cat. No. CS-0326225
  • Purity ≥95%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₂N₂O₃S
  • Molecular Weight 298.40
  • Synonym(s) Tert-butyl 4-[4-(hydroxymethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate
  • SMILES CC(C)(C)OC(=O)N1CCC(CC1)C2=NC(=CS2)CO

Synthesis

  • Route1
    • Ethyl 2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylate|CS-0200004
      365413-31-6
    • ~81%
    • Tert-butyl 4-(4-(hydroxymethyl)thiazol-2-yl)piperidine-1-carboxylate|CS-0326225
      864068-79-1

    References

    • BRISTOL-MYERS SQUIBB COMPANY; UNIVERSITÉ DE MONTRÉAL; BANVILLE, Jacques; RÉMILLARD, Roger; RUEDIGER, Edward H.; DEON, Daniel H.; GAGNON, Marc; DUBÉ, Laurence; GUY, Julia; PRIESTLEY, Eldon Scott; POSY, Shoshana L.; MAXWELL, Brad D.; WONG, Pancras C. Patent: WO2013/163279 A1, 2013 ; Location in patent: Paragraph 00312 ;
  • Route2

    References

    • BRISTOL-MYERS SQUIBB COMPANY; UNIVERSITÉ DE MONTRÉAL; BANVILLE, Jacques; RÉMILLARD, Roger; RUEDIGER, Edward H.; DEON, Daniel H.; GAGNON, Marc; DUBÉ, Laurence; GUY, Julia; PRIESTLEY, Eldon Scott; POSY, Shoshana L.; MAXWELL, Brad D.; WONG, Pancras C. Patent: WO2013/163279 A1, 2013 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   62.66
  • LogP   2.7499
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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