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CS-W001157 4
Total: USD 88.00

Ethyl 2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylate

  • CAS No. 365413-31-6

  • Cat. No. CS-0200004
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylate|CS-0200004

Structure of 365413-31-6

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General Information

  • CAS No. 365413-31-6
  • Cat. No. CS-0200004
  • Purity ≥97%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₄N₂O₄S
  • Molecular Weight 340.44
  • Synonym(s) tert-Butyl-4-[4-(ethoxycarbonyl)-1,3-thiazol-2-yl]-piperizine-1-carboxylate
  • SMILES CCOC(=O)C1=CSC(=N1)C2CCN(CC2)C(=O)OC(C)(C)C

Synthesis

  • Route1

    References

    • METRIS THERAPEUTICS LIMITED Patent: WO2004/58750 A1, 2004 ; Location in patent: Page 31-32; 30 ;
  • Route2
    • 1-Boc-4-(4-Ethoxycarbonyl-4,5-Dihydrothiazol-2-yl)piperidine|CS-0766356
      881197-94-0
    • ~29%
    • Ethyl 2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylate|CS-0200004
      365413-31-6

    References

    • 4SC AG Patent: EP1834954 A1, 2007 ; Location in patent: Page/Page column 21 ; EP 1834954 A1
  • Route3
    • null|null
      1192878-45-7
    • ~83%
    • Ethyl 2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylate|CS-0200004
      365413-31-6

    References

    • Merck Patent Gesellschaft Mit Beschrankter Haftling Patent: US2011/60007 A1, 2011 ; Location in patent: Page/Page column 20 ; US 20110060007 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   68.73
  • LogP   3.4343
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   3

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